[兔支气管肺组织非特异性炎症过程发展中表面活性脂质抗自由基活性的变化]
[Change in the antiradical activity of surfactant lipids during the development of nonspecific inflammatory processes in rabbit bronchopulmonary tissue].
作者信息
Panevskaia G N, Iarosh A M, Nesterov E N
出版信息
Vopr Med Khim. 1978 May-Jun;24(3):412-5.
PMID:580818
Abstract
Content of total lipids, phospholipids and cholesterol was estimated in surface-active fraction isolated from rabbit lungs. The surface activity and antiradical properties were decreased in the fraction simultaneously with a decrease in phospholipid contents in the course of development of inflammatory process in bronchopulmonary tissue. These data suggested that the antiradical activity, which is essential for protection of the surface-active fraction against free radical peroxidation, was mainly due to the phospholipid component.
摘要
对从兔肺中分离出的表面活性部分中的总脂质、磷脂和胆固醇含量进行了估算。在支气管肺组织炎症过程发展过程中，该部分的表面活性和抗自由基特性随着磷脂含量的降低而同时降低。这些数据表明，对于保护表面活性部分免受自由基过氧化至关重要的抗自由基活性主要归因于磷脂成分。
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