Verbolovich V P, Petrenko E P, Podgornyĭ Iu K
Vopr Med Khim. 1985 Sep-Oct;31(5):65-8.
Surface-active substances of lung tissue, covering the alveoli, resembled the biological membranes in their structure. Their composition was controlled, among the other factors, also by free radical oxidation reactions. Under conditions of circulatory hypoxia the activity of antioxidative enzymes correlated with the alterations in antioxidative activity, with the rates of spontaneous and inducible lipid peroxidation in lung surfactants. As surfactant exhibited a limited antioxidative activity important for resistance of alveolar pneumocytes, their functions may be controlled by various exogenous antioxidants.
覆盖在肺泡表面的肺组织表面活性物质，其结构类似于生物膜。在其他因素中，其组成也受自由基氧化反应的控制。在循环性缺氧的情况下，抗氧化酶的活性与抗氧化活性的改变、肺表面活性剂中自发和诱导性脂质过氧化的速率相关。由于表面活性剂表现出对肺泡肺细胞抗性很重要的有限抗氧化活性，其功能可能受各种外源性抗氧化剂的控制。
