Pike R M
Arch Pathol Lab Med. 1978 Jul;102(7):333-6.
Over 4,000 cases of laboratory-associated infection have been recorded. Some of the agents involved often in the past have been less frequently the cause of such infection in recent years, and some agents are more likely to infect those working with them than others. Pipetting, the use of a needle and syringe, and spills have been most frequently involved in accidents resulting in infection, but in the majority of cases no recognized accident occurred. In these instances, infectious aerosols, produced in various ways, are probably the most frequent causes of laboratory-associated infection. The introduction of protective devices and emphasis on safe procedures seem to be reducing the risk of accidental infection. Although work with tumor viruses and recombinant DNA research may not be as hazardous as was originally feared, continued caution and surveillance is advised.
已记录到4000多例实验室相关感染病例。过去一些常涉及的病原体近年来引发此类感染的频率降低，且一些病原体比其他病原体更易感染接触它们的工作人员。移液、使用针头和注射器以及溢出物最常导致感染事故，但在大多数情况下并未发生可识别的事故。在这些情况下，通过各种方式产生的感染性气溶胶可能是实验室相关感染最常见的原因。防护装置的引入和对安全程序的重视似乎正在降低意外感染的风险。尽管从事肿瘤病毒研究和重组DNA研究可能不像最初担心的那样危险，但仍建议持续保持谨慎并进行监测。
