Gamble D R, Taylor K W
Br Med J. 1969 Sep 13;3(5671):631-3. doi: 10.1136/bmj.3.5671.631.
A seasonal incidence in the onset of insulin-dependent diabetes in patients under 30 years of age has been suggested from the analysis of data derived from the clinic registers of two diabetic clinics. The increased incidence occurred in summer, autumn, and winter, with a peak in the autumn. A significant variation in annual totals of new cases of diabetes seen could not be demonstrated or excluded, but the pattern of the variation present showed significant positive correlation with the annual prevalence data for Coxsackie virus type B4, but not for other types of virus infection.
通过对两家糖尿病诊所临床登记数据的分析，有人提出30岁以下胰岛素依赖型糖尿病患者发病存在季节性。发病率增加出现在夏季、秋季和冬季，秋季达到峰值。虽然无法证实或排除所观察到的糖尿病新发病例年度总数的显著变化，但所呈现的变化模式与B4型柯萨奇病毒的年度流行数据呈显著正相关，而与其他类型的病毒感染无关。
