柯萨奇病毒与糖尿病
Coxsackie viruses and diabetes mellitus.
作者信息
Gamble D R, Taylor K W, Cumming H
出版信息
Br Med J. 1973 Nov 3;4(5887):260-2. doi: 10.1136/bmj.4.5887.260.
Abstract
Serum specimens from 162 patients with insulin-dependent diabetes of recent onset and 319 controls were tested for neutralizing antibodies to Coxsackie viruses types B1 to B5. Antibody to type B4 virus was more often found in diabetics than in controls, particularly in the 10-19 year age group. Though controls were not matched for geographical area it was thought that this was unlikely to explain the difference found. The month of onset of diabetes in the patients studied showed a pronounced seasonal incidence, which resembled that found in earlier studies.
摘要
对162例近期发病的胰岛素依赖型糖尿病患者和319例对照者的血清标本进行了检测，以查找针对B1至B5型柯萨奇病毒的中和抗体。在糖尿病患者中发现B4型病毒抗体的情况比对照者更为常见，尤其是在10 - 19岁年龄组。尽管对照者在地理区域上未进行匹配，但认为这不太可能解释所发现的差异。所研究患者的糖尿病发病月份显示出明显的季节性发病率，这与早期研究中发现的情况相似。
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本文引用的文献
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Seasonal incidence of diabetes mellitus.糖尿病的季节性发病率。
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Viral antibodies in diabetes mellitus.糖尿病中的病毒抗体。
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Anti-pancreatic cellular hypersensitivity in diabetes mellitus.糖尿病中的抗胰腺细胞超敏反应。
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Viral pancreatitis: ultrastructural pathological effects of Coxsackievirus B3 infection in newborn mouse pancreas.病毒性胰腺炎：柯萨奇病毒B3感染对新生小鼠胰腺的超微结构病理影响
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