三倍体青蛙肿瘤多潜能细胞核的移植。
Transplantation of pluripotential nuclei from triploid frog tumors.
作者信息
McKinnell R G, Deggins B A, Labat D D
出版信息
Science. 1969 Jul 25;165(3891):394-6. doi: 10.1126/science.165.3891.394.
PMID:5815255
Abstract
Renal tumors were produced by injection of a cell fraction of a tumor into triploid tadpoles of Rana pipiens before they began feeding. Triploid tumor cells were dissociated and transplanted into activated and enucleated eggs. Pluripotency of the implanted nuclei was evidenced by the formation of swimming triploid tadpoles.
摘要
在食用前，将肿瘤的细胞组分注射到牛蛙的三倍体蝌蚪中，从而诱发肾肿瘤。将三倍体肿瘤细胞解离并移植到激活的去核卵中。植入细胞核的多能性通过游动的三倍体蝌蚪的形成得到证明。
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