Campbell C D, Brooks D H, Siewers R D, Peel R L, Bahnson H T
Surg Gynecol Obstet. 1979 Apr;148(4):525-30.
Expanded polytetrafluoroethylene has been used successfully for femoropopliteal bypass, aortopulmonary bypass and as a venous substitute. Thirteen patients with impending limb loss had extra-anatomic bypasses with expanded polytetrafluoroethylene. Five patients with unilateral iliac disease had femorofemoral bypass for impending limb loss, and five debilitated patients underwent axillofemoral and bifemoral bypass for limb salvage. Nine of ten patients had salvage of the extremities. Three patients had extended profundoplasty, two combined with polytetrafluoroethylene femoropopliteal bypass to isolated popliteal artery segments. Two of these patients had limb salvage. The patency rate is 92 per cent, and the limb salvage rate is 85 per cent in this difficult group of patients. The follow-up period extends to 28 months, and 12 patients are beyond one year. In six patients, polytetrafluoroethylene carotid subclavian bypass was performed for the subclavian steal syndrome; all patients had relief of the symptoms. One patient underwent axillary-axillary bypass with excellent results. Expanded microporous polytetrafluoroethylene with its high patency, shortened operating time, biocompatibility and excellent tissue incorporation is an excellent arterial substitute. The pliability and no requirement for preclotting make polytetrafluoroethylene ideally suited for patch angioplasty and suturing in areas difficult to expose.
膨体聚四氟乙烯已成功用于股腘动脉搭桥、主肺动脉搭桥及作为静脉替代物。13例即将失去肢体的患者接受了膨体聚四氟乙烯的解剖外搭桥术。5例单侧髂血管疾病患者因即将失去肢体接受了股股动脉搭桥术，5例身体虚弱的患者接受了腋股动脉和双股动脉搭桥术以挽救肢体。10例患者中有9例肢体得以挽救。3例患者接受了扩大的股深动脉成形术，其中2例联合膨体聚四氟乙烯股腘动脉搭桥至孤立的腘动脉段。这2例患者肢体得以挽救。在这群病情较重的患者中，通畅率为92%，肢体挽救率为85%。随访期长达28个月，12例患者随访时间超过1年。6例患者因锁骨下动脉窃血综合征接受了膨体聚四氟乙烯颈动脉-锁骨下动脉搭桥术；所有患者症状均缓解。1例患者接受了腋腋动脉搭桥术，效果良好。具有高通畅率、缩短手术时间、生物相容性及良好组织整合性的膨体微孔聚四氟乙烯是一种优良的动脉替代物。其柔韧性及无需预凝的特性使其非常适合于在难以暴露的区域进行补片血管成形术和缝合。
