Petty T L, Silvers G W, Paul G W, Stanford R E
Chest. 1979 May;75(5):571-4. doi: 10.1378/chest.75.5.571.
We have examined the lungs from five patients who died with the adult respiratory distress syndrome (ARDS). Pressure volume curves were obtained and bronchoalveolar lavage fluid was studied on a surface balance. The pressure volume curves revealed reduced compliance compared to normal or near normal lungs. A significant loss of volume was also found. The data obtained from the surface balance studies show a normal range of minimum surface tension when compared to "normals," but the ARDS lung lavage fluid revealed an increase in surface film compressibility relative to "normal." The increased compressibility may be an important factor contributing to the stiff lungs of patients with the adult respiratory distress syndrome.
我们检查了五例死于成人呼吸窘迫综合征（ARDS）患者的肺部。获取了压力-容积曲线，并在表面天平上对支气管肺泡灌洗液进行了研究。与正常或接近正常的肺部相比，压力-容积曲线显示顺应性降低。还发现有明显的容积损失。表面天平研究获得的数据表明，与“正常”情况相比，最小表面张力在正常范围内，但ARDS肺灌洗液相对于“正常”情况显示表面膜压缩性增加。增加的压缩性可能是导致成人呼吸窘迫综合征患者肺部僵硬的一个重要因素。
