胃复安对术后肠梗阻的影响。一项随机双盲研究。
The effects of metoclopramide on postoperative ileus. A randomized double-blind study.
作者信息
Davidson E D, Hersh T, Brinner R A, Barnett S M, Boyle L P
出版信息
Ann Surg. 1979 Jul;190(1):27-30. doi: 10.1097/00000658-197907000-00006.
Abstract
Metoclopramide or placebo was administered postoperatively in a randomized, double-blind fashion to 115 patients undergoing laparotomy. The effect of metoclopramide on postoperative adynamic ileus (PAI) was evaluated. The patients were stratified into two groups: Group A--those with laparotomy without a gastrointestinal anastomosis or ostomy procedure, and group B--those with laparotomy undergoing an anastomosis or ostomy procedure. Metoclopramide reduced nausea and emesis postoperatively. However, the only significant effect on postoperative adynamic ileus was an earlier return to tolerance of solid foods in the patients in Group A.
摘要
对115例行剖腹手术的患者，术后以随机、双盲方式给予甲氧氯普胺或安慰剂。评估了甲氧氯普胺对术后动力性肠梗阻（PAI）的影响。患者被分为两组：A组——行剖腹手术但未进行胃肠吻合或造口术的患者，B组——行剖腹手术并进行吻合或造口术的患者。甲氧氯普胺减少了术后恶心和呕吐。然而，对术后动力性肠梗阻唯一显著的影响是A组患者更早恢复对固体食物的耐受。
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