大鼠、兔和豚鼠不同胎龄时母体与胎儿之间的电位差。
Potential differences between mother and foetus at different gestational ages in the rat, rabbit and guinea-pig.
作者信息
Mellor D J
出版信息
J Physiol. 1969 Oct;204(2):395-405. doi: 10.1113/jphysiol.1969.sp008919.
Abstract
- Potential differences associated with fluid compartments of rat, rabbit and guinea-pig conceptuses have been measured. [Na(+)] and [Cl(-)] in maternal plasma and amniotic fluid from these three species were also determined.2. Transplacental potential differences of about 15 mV (foetus positive) were found in the rat, of approximately 0 mV in the rabbit, and of about 18 mV (foetus negative) in the guinea-pig.3. Amniotic fluid potential differences appeared to arise indirectly from the transplacental potential difference in the rat, from the foetal gastric mucosa in the rabbit, and possibly from the foetal gastric mucosa and indirectly from the placenta in the guinea-pig.4. The results are discussed in the context of Na(+) transfer to the foetus, and on this basis tend to question the general assumption that almost all Na(+) reaching the foetus passes across the placenta.
摘要
已测量了大鼠、兔和豚鼠胚胎各体液间的电位差。还测定了这三个物种母体血浆和羊水中的[Na⁺]和[Cl⁻]。
发现大鼠的经胎盘电位差约为15 mV（胎儿为正），兔的约为0 mV，豚鼠的约为18 mV（胎儿为负）。
羊水电位差在大鼠中似乎间接源自经胎盘电位差，在兔中源自胎儿胃黏膜，在豚鼠中可能源自胎儿胃黏膜且间接源自胎盘。
结合Na⁺向胎儿的转运对结果进行了讨论，在此基础上，倾向于质疑几乎所有到达胎儿的Na⁺都通过胎盘这一普遍假设。
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