Pye R J, Burton J L
Lancet. 1976 Jun 5;1(7971):1211-2. doi: 10.1016/s0140-6736(76)92160-7.
A double-blind trial in twenty-nine patients with rosacea showed that, after 6 weeks' treatment, metronidazole was therapeutically superior to a placebo (P less than 0-02). It was particularly effective against papules and pustules. The mode of action of metronidazole and other antibiotics in rosacea is not known.
一项针对29名酒渣鼻患者的双盲试验表明,经过6周治疗后,甲硝唑在治疗效果上优于安慰剂(P小于0.02)。它对丘疹和脓疱特别有效。甲硝唑和其他抗生素在酒渣鼻治疗中的作用方式尚不清楚。