Tamm I, Eggers H J
Calif Med. 1965 Nov;103(5):305-9.
There are more than 300 immunological types of viruses that infect man, but most are members of only eight major groups, each group characterized by distinguishing physical and chemical features. Chemical inhibitors have been discovered which are selectively directed against members of individual groups of viruses. These inhibitors interfere with virus-specific processes and have no effects on host cell metabolism at concentrations sufficient to prevent or stop virus multiplication. The biochemical basis of such selective action is understood in some cases. In addition, synthetic chemicals and biological products are known that inhibit members of several groups of viruses. The basis of their selective action is not clear.
有300多种免疫类型的病毒可感染人类，但大多数仅属于八个主要类别，每个类别都有独特的物理和化学特征。已经发现了化学抑制剂，它们可选择性地作用于个别病毒类别。这些抑制剂干扰病毒特异性过程，并且在足以预防或阻止病毒繁殖的浓度下对宿主细胞代谢没有影响。在某些情况下，这种选择性作用的生化基础是已知的。此外，已知合成化学物质和生物制品可抑制几类病毒。它们选择性作用的基础尚不清楚。
