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颅内动脉瘤的自然病史:急性期和长期的再出血率及其对手术治疗的意义。

The natural history of intracranial aneurysms: rebleeding rates during the acute and long term period and implication for surgical management.

作者信息

Jane J A, Winn H R, Richardson A E

出版信息

Clin Neurosurg. 1977;24:176-84. doi: 10.1093/neurosurgery/24.cn_suppl_1.176.

Abstract
  1. In the first 6 months, at least 50% of the patients with untreated anterior and posterior communicating artery aneurysms will rebleed. 2. Thereafter, the rate of rebleeding is not less than 3%/year with two-thirds of these late hemorrhages resulting in a mortality. 3. Carotid ligation for posterior communicating aneurysms protects against a high rate of rebleeding for 6 months, but thereafter the rate is not different from the course of untreated aneurysms. 4. On the basis of these first three points and a review of the literature, a theory is proposed that incidental and symptomatic unruptured aneurysms, multiple unruptured aneurysms, and subarachnoid hemorrhage where no lesion is demonstrable, have a natural history similar to that of the untreated aneurysm that survives at 6 months. Namely, we would predict a yearly rebleed rate of not less than 3%/year.
摘要
  1. 在最初6个月内,未治疗的前交通动脉和后交通动脉动脉瘤患者中至少50%会再次出血。2. 此后,再次出血率每年不少于3%,其中三分之二的晚期出血会导致死亡。3. 后交通动脉瘤的颈动脉结扎可在6个月内预防高再次出血率,但此后该比率与未治疗动脉瘤的病程无异。4. 根据前三点及文献综述,提出一种理论,即偶然发现的和有症状的未破裂动脉瘤、多发未破裂动脉瘤以及未发现病变的蛛网膜下腔出血,其自然病程与存活6个月的未治疗动脉瘤相似。也就是说,我们预计每年再次出血率不少于3%。

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