红斑狼疮乳胶试验与抗核因子免疫荧光法的比较
Lupus erythematosus latex tests compared with the immunofluorescence method for antinuclear factor.
作者信息
Chapman J C
出版信息
Am J Med Technol. 1976 May;42(5):154-7.
Two commercially available lupus erythematosus (LE) latex tests were compared against positive antinuclear antibody (ANF) sera of known titers. The Lederle SLE Latex Test Kit was found to be more specific and relatively more sensitive, particulary with high ANF titers, than the Hyland LE Test Kit. The latex test is a rapid, simple method which, when positive, can be suggestive of systemic lupus erythematosus (SLE) or other collagen disease. However, at present this test cannot replace the immunofluorescence method for detecting ANF. Where there is any clinical suggestion of SLE or a related condition, all negative results should be tested by immunofluorescence methods.
将两种市售的红斑狼疮（LE）乳胶试验与已知滴度的阳性抗核抗体（ANF）血清进行了比较。结果发现，与海兰LE检测试剂盒相比，莱德勒系统性红斑狼疮乳胶检测试剂盒更具特异性，相对更敏感，尤其是对于高ANF滴度的血清。乳胶试验是一种快速、简便的方法，呈阳性时可能提示系统性红斑狼疮（SLE）或其他胶原病。然而，目前该试验不能替代检测ANF的免疫荧光法。凡有SLE或相关病症的临床提示时，所有阴性结果均应用免疫荧光法进行检测。
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