Bryniak C, Lisiewicz J, Seibert K
Folia Haematol Int Mag Klin Morphol Blutforsch. 1976;103(1):43-55.
Activity of acid phosphatase, beta-glucuronidase, and beta-glucosaminidase was determined in peripheral blood lymphocytes of 29 premature and 20 term infants with the use of cytochemical methods. The results were expressed semiquantitatively and included the total count of enzyme-positive and the enzyme-negative lymphocytes as well as the intracellular content of enzyme-positive and enzyme-negative lysosomal granules. The premature infant exhibited significantly lower activity of all the studied enzymes than the term infants. It thus argues in favour of the opinion that the lysosomal apparatus in lymphocytes undergoes development in the course of fetal maturation of the immune system. Evaluation of the activity of lysosomal enzymes in lymphocytes can serve as an indicator of fetal maturity and immunological status.
采用细胞化学方法测定了29例早产儿和20例足月儿外周血淋巴细胞中酸性磷酸酶、β-葡萄糖醛酸酶和β-氨基葡萄糖苷酶的活性。结果以半定量方式表示，包括酶阳性和酶阴性淋巴细胞的总数以及酶阳性和酶阴性溶酶体颗粒的细胞内含量。早产儿所有研究酶的活性均显著低于足月儿。因此，这支持了淋巴细胞中的溶酶体装置在免疫系统胎儿成熟过程中会发生发育的观点。评估淋巴细胞中溶酶体酶的活性可作为胎儿成熟度和免疫状态的指标。
