附加瓣膜病变对主动脉瓣狭窄患者左心室射血时间的影响。
Effect of additional valve lesions on left ventricular ejection time in aortic stenosis.
作者信息
Kligfield P, Goldberg H, Kline S A, Scheidt S
出版信息
Br Heart J. 1977 Nov;39(11):1259-64. doi: 10.1136/hrt.39.11.1259.
Rate-corrected left ventricular ejection time was measured from the aortic pressure tracings of 171 catheterised patients with aortic valve area less than or equal to 1.2 cm2. In 50 patients with pure aortic stenosis, left ventricular ejection time in increased with decreasing valve area and was significantly higher (468 +/- 5 ms, mean +/- SEM) than in 13 normal subjects (435 +/- 5 ms). Additional aortic regurgitation in 72 patients further increased the left ventricular ejection time to 484 +/- 4 ms. Significant mitral stenosis (mitral valve are less than or equal to 1.2 cm2) in 6 patients with aortic stenosis and 33 patients with aortic stenosis and regurgitation reduced the left ventricular ejection time to normal. Similarly, severe mitral regurgitation in 3 patients with aortic stenosis and regurgitation reduced left ventricular ejection time to normal, though slight or moderate mitral regurgitation in 4 of these patients did not. These data show that the prolonged left ventricular ejection time in aortic valve disease may be restored to normal in the presence of coexisting significant mitral disease.
从171例主动脉瓣面积小于或等于1.2平方厘米的导管插入术患者的主动脉压力描记图中测量经心率校正的左心室射血时间。在50例单纯主动脉瓣狭窄患者中，左心室射血时间随瓣膜面积减小而增加，且显著高于13名正常受试者（468±5毫秒，平均值±标准误）（435±5毫秒）。72例合并主动脉瓣反流的患者，其左心室射血时间进一步增加至484±4毫秒。6例主动脉瓣狭窄患者和33例主动脉瓣狭窄合并反流患者中存在显著二尖瓣狭窄（二尖瓣面积小于或等于1.2平方厘米），使左心室射血时间恢复正常。同样，3例主动脉瓣狭窄合并反流患者中的严重二尖瓣反流使左心室射血时间恢复正常，不过其中4例患者的轻度或中度二尖瓣反流则未使其恢复正常。这些数据表明，在并存显著二尖瓣疾病的情况下，主动脉瓣疾病中延长的左心室射血时间可能恢复正常。
Zotero 插件