用于检测抗B族链球菌Ia、Ib、Ic、II和III型特异性抗体的放射免疫测定法。
Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III.
作者信息
Wilkinson H W, Jones W L
出版信息
J Clin Microbiol. 1976 May;3(5):480-5. doi: 10.1128/jcm.3.5.480-485.1976.
Abstract
The object of this study was to develop a test that would measure antibodies directed against group B streptococcal types Ia, Ib, Ic, II, and III. The type-specific carbohydrate antigens were purified, labeled with 125I, and used to develop a radioimmunoassay. This procedure should be particularly useful in testing human sera for group B type-specific antibodies, since it requires very small quantities of antigens and measures primary type antigen-antibody interactions.
摘要
本研究的目的是开发一种能检测针对B族链球菌Ia、Ib、Ic、II和III型抗体的检测方法。将型特异性碳水化合物抗原纯化，用125I标记，并用于开发放射免疫测定法。该方法在检测人血清中B族型特异性抗体时应特别有用，因为它所需抗原量极少，且能检测主要的型抗原-抗体相互作用。
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