Kimura D
Brain. 1977 Sep;100(3):527-42. doi: 10.1093/brain/100.3.527.
Specialization of function in the left hemisphere of man, as compared with the right, was studied with special reference to the nature of the impairments seen after left-hemisphere damage. Patients with unilateral lesions of the left or the right hemisphere were compared in the acquisition and subsequent performance of a manual skill requiring several hand movements. Patients with left-hemisphere damage were further subdivided into aphasic and non-aphasic groups. Patients with left-hemisphere damage were further subdivided into aphasic and non-aphasic groups. Patients with left-hemisphere damage, whether aphasic or not, were impaired in the acquisition of the task, relative to patients with right hemisphere damage, although aphasics were most severely impaired. Analysis of the errors made during acquisition indicated that perseverative errors and unique errors (unrelated movements) differentiated the left and right groups, but that sequencing errors did not. It was concluded that a major function of the left hemisphere is the control of changes in limb or articulatory posture, and that its complex verbal and praxic functions are derived from such control.
与右半球相比，对人类左半球功能特化的研究特别参考了左半球损伤后出现的损伤性质。比较了左半球或右半球单侧损伤的患者在学习一项需要多次手部动作的手工技能以及后续表现方面的情况。左半球损伤的患者进一步分为失语组和非失语组。左半球损伤的患者，无论是否失语，相对于右半球损伤的患者，在学习任务时都受到了损害，尽管失语患者受损最为严重。对学习过程中所犯错误的分析表明，持续性错误和独特错误（无关动作）区分了左、右两组，但顺序错误并没有。得出的结论是，左半球的主要功能是控制肢体或关节姿势的变化，其复杂的语言和实践功能源于这种控制。
