贫血、缺铁与运动：人体受试者的扩展研究。

Anaemia, iron deficiency and exercise: extended studies in human subjects.

Charlton R W, Derman D, Skikne B, Torrance J D, Lynch S R, Sayers M H, Zwi S, Goldman H I, Van As A, Margo G, Schneider J T, Bothwell T H

Clin Sci Mol Med. 1977 Dec;53(6):537-41. doi: 10.1042/cs0530537.

Abstract

Ventilation and cardiac frequency were measured during repeated treadmill exercise in three healthy subjects over 36 weeks, before, during and after iron-deficiency anaemia was produced and after iron treatment. The haemoglobin and 2,3-diphosphoglycerate concentrations and the oxygen-binding (P50) were measured. 2. There was an inverse relationship between the haemoglobin concentrations and the 2,3-diphosphoglycerate concentrations and the P50 values. 3. The mean cardiac frequencies during the fourth to tenth minutes of exercise showed a negative correlation with the haemoglobin concentrations in all three subjects, and the mean minute ventilations in two of them.

摘要

在三名健康受试者中，于36周内重复进行跑步机运动期间，在缺铁性贫血产生之前、期间和之后以及铁治疗之后，测量通气和心率。测量血红蛋白、2,3-二磷酸甘油酸浓度以及氧结合力（P50）。2. 血红蛋白浓度与2,3-二磷酸甘油酸浓度及P50值之间呈负相关。3. 在所有三名受试者中，运动第四至十分钟期间的平均心率与血红蛋白浓度呈负相关，在其中两名受试者中，平均每分通气量与血红蛋白浓度也呈负相关。