Spoor R P, Jackson D B
Science. 1966 Nov 11;154(3750):782. doi: 10.1126/science.154.3750.782.
Experiments were performed at two time points in the 24hour cycle to determine whether isolated right atria of rats would vary in sensitivity, with a circadian rhythm, to two concentrations of acetylcholine. The beating rate of the atria decreased more in response to the drug if the atria were isolated at 1100 than if isolated at 2300 hours.
在24小时周期中的两个时间点进行了实验，以确定大鼠离体右心房对两种浓度乙酰胆碱的敏感性是否会随昼夜节律而变化。如果心房在11点分离，其对药物的反应导致的跳动速率下降比在23点分离时更多。
