Adelusi B
J Trop Med Hyg. 1977 Jul;80(7):152-4.
Genetic factors have been suggested as having a possible aetiological role in the incidence of carcinoma of the cervix. With the high frequency of carcinoma of the cervix in Ibadan as well as the high incidence of sickle-cell trait, the haemoglobin genotypes and ABO blood groups were analysed in patients managed for carcinoma of the cervix uteri in the University College Hospital, Ibadan. No significant association was found between any haemoglobin genotype or blood group and carcinoma of the cervix. The protection afforded against malaria by the haemoglobin S trait does not seem to protect against the development of invasive carcinoma of the cervix.
遗传因素被认为可能在宫颈癌的发病中具有病因学作用。鉴于伊巴丹宫颈癌的高发病率以及镰状细胞性状的高发生率，对伊巴丹大学学院医院接受子宫颈癌治疗的患者的血红蛋白基因型和ABO血型进行了分析。未发现任何血红蛋白基因型或血型与宫颈癌之间存在显著关联。血红蛋白S性状对疟疾的保护作用似乎并未预防浸润性宫颈癌的发生。
