来自绳状青霉的一种抗病毒物质。VII. 关于确定注射海伦宁的小鼠所表现出的抗被动免疫效应的物质是否为干扰素的尝试。
An antiviral substance from Penicillium funiculosum. VII. An attempt to determine whether the material responsible for the antipassive immunity effect exhibited by mice injected with helenine is an interferon.
作者信息
Shope R E
出版信息
J Exp Med. 1966 Nov 1;124(5):915-9. doi: 10.1084/jem.124.5.915.
Abstract
Helenine, NDV, and statolon, all known inducers of interferon in mice, all exerted a marked antiviral effect against Semliki Forest virus. This AV effect was, so far as can be demonstrated, mediated through, the induced interferon. The same three materials also exerted a marked antipassive immunity effect. All the evidence that can be brought to bear indicates that this API effect like the AV effect is mediated through interferon known to be induced by the three materials. If the API effect does indeed have interferon as its basis, this represents a new and totally unsuspected action of interferon.
摘要
海伦宁、新城疫病毒和杀菌素都是已知的小鼠干扰素诱导剂，它们对Semliki森林病毒均有显著的抗病毒作用。就目前所能证明的而言，这种抗病毒作用是通过诱导产生的干扰素介导的。同样这三种物质也具有显著的抗被动免疫作用。所有能找到的证据都表明，这种抗被动免疫作用与抗病毒作用一样，是通过已知由这三种物质诱导产生的干扰素介导的。如果抗被动免疫作用确实以干扰素为基础，那么这代表了干扰素一种全新的、完全未被料到的作用。
相似文献
1
An antiviral substance from Penicillium funiculosum. VII. An attempt to determine whether the material responsible for the antipassive immunity effect exhibited by mice injected with helenine is an interferon.来自绳状青霉的一种抗病毒物质。VII. 关于确定注射海伦宁的小鼠所表现出的抗被动免疫效应的物质是否为干扰素的尝试。
J Exp Med. 1966 Nov 1;124(5):915-9. doi: 10.1084/jem.124.5.915.
2
An antiviral substance from Penicillium funiculosum. VI. Prevention of the establishment of passive immunity to Semliki Forest virus infection in mice by Helenine.来自绳状青霉的一种抗病毒物质。VI. 海伦宁对小鼠感染辛德毕斯森林病毒后被动免疫建立的预防作用
J Exp Med. 1966 Jul 1;124(1):15-31. doi: 10.1084/jem.124.1.15.
3
An antiviral substance from Penicillium funiculosum. II. Effect of helenine upon infection in mice with Semliki Forest virus.一种来自绳状青霉的抗病毒物质。II. 海伦宁对小鼠感染Semliki森林病毒的影响。
J Exp Med. 1953 May;97(5):627-38. doi: 10.1084/jem.97.5.627.
4
An antiviral substance from Penicillium funiculosum. IV. Inquiry into the mechanism by which helenine exerts its antiviral effect.来自绳状青霉的一种抗病毒物质。IV. 对海伦宁发挥其抗病毒作用机制的探究。
J Exp Med. 1966 Feb 1;123(2):213-27. doi: 10.1084/jem.123.2.213.
5
An antiviral substance from Penicillium funiculosum. V. Induction of interferon by helenine.来自绳状青霉的一种抗病毒物质。V. 海伦宁对干扰素的诱导作用
J Exp Med. 1966 Apr 1;123(4):577-84. doi: 10.1084/jem.123.4.577.
6
An antiviral substance from Penicillium funiculosum. I. Effect upon infection in mice with swine influenza virus and Columbia SK encephalomyelitis virus.一种来自绳状青霉的抗病毒物质。I. 对小鼠感染猪流感病毒和哥伦比亚SK脑脊髓炎病毒的影响。
J Exp Med. 1953 May;97(5):601-25. doi: 10.1084/jem.97.5.601.
7
The presence in Penicillium funiculosum of an inhibitor to the antiviral agent helenine.绳状青霉中存在一种对抗病毒剂海伦宁的抑制剂。
J Exp Med. 1966 Mar 1;123(3):505-8. doi: 10.1084/jem.123.3.505.
8
An antiviral substance from Penicillium funiculosum. III. General properties and characteristics of helenine.一种来自绳状青霉的抗病毒物质。III. 海伦宁的一般性质和特征。
J Exp Med. 1953 May;97(5):639-50. doi: 10.1084/jem.97.5.639.
9
Antiviral activity of double stranded RNA and virus-like particles from Penicillium stoloniferum.
Nature. 1970 Aug 1;227(5257):504-5. doi: 10.1038/227504a0.
10
Target-organ treatment of neurotropic virus disease with interferon inducers.用干扰素诱导剂对嗜神经病毒疾病进行靶器官治疗。
Infect Immun. 1972 Nov;6(5):819-23. doi: 10.1128/iai.6.5.819-823.1972.
引用本文的文献
1
Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.在基于细胞的高通量筛选中鉴定用于DNA双链断裂修复抑制剂的新型放射增敏剂。
Mol Cancer Ther. 2015 Feb;14(2):326-42. doi: 10.1158/1535-7163.MCT-14-0765. Epub 2014 Dec 15.
2
Protease inhibitors in inflammatory synovial effusions.炎性滑膜积液中的蛋白酶抑制剂
Ann Rheum Dis. 1981 Feb;40(1):55-9. doi: 10.1136/ard.40.1.55.
本文引用的文献
1
INTERFERON PRODUCTION INDUCED BY STATOLON.斯他洛菌素诱导的干扰素产生
Proc Natl Acad Sci U S A. 1964 Sep;52(3):741-4. doi: 10.1073/pnas.52.3.741.
2
CIRCULATING INTERFERON IN MICE AFTER INTRAVENOUS INJECTION OF VIRUS.静脉注射病毒后小鼠体内的循环干扰素
Science. 1963 Sep 13;141(3585):1061-3. doi: 10.1126/science.141.3585.1061.
3
An antiviral substance from Penicillium funiculosum. VI. Prevention of the establishment of passive immunity to Semliki Forest virus infection in mice by Helenine.来自绳状青霉的一种抗病毒物质。VI. 海伦宁对小鼠感染辛德毕斯森林病毒后被动免疫建立的预防作用
J Exp Med. 1966 Jul 1;124(1):15-31. doi: 10.1084/jem.124.1.15.
4
An antiviral substance from Penicillium funiculosum. V. Induction of interferon by helenine.来自绳状青霉的一种抗病毒物质。V. 海伦宁对干扰素的诱导作用
J Exp Med. 1966 Apr 1;123(4):577-84. doi: 10.1084/jem.123.4.577.
5
An antiviral substance from Penicillium funiculosum. IV. Inquiry into the mechanism by which helenine exerts its antiviral effect.来自绳状青霉的一种抗病毒物质。IV. 对海伦宁发挥其抗病毒作用机制的探究。
J Exp Med. 1966 Feb 1;123(2):213-27. doi: 10.1084/jem.123.2.213.
Zotero 插件