血清在兔单核细胞内对葡萄球菌的杀伤作用。
Role of serum in the intracellular killing of staphylococci in rabbit monocytes.
作者信息
Shayegani M G, Mudd S
出版信息
J Bacteriol. 1966 Apr;91(4):1393-8. doi: 10.1128/jb.91.4.1393-1398.1966.
Shayegani, Mehdi G. (U.S. Veterans Administration Hospital, Philadelphia, Pa.), and Stuart Mudd. Role of serum in the intracellular killing of staphylococci in rabbit monocytes. J. Bacteriol. 91:1393-1398. 1966.-Although some intracellular killing occurs in rabbit monocytes with heated normal serum or even in monocytes washed three times with Hanks' solution and with staphylococci not exposed to serum, efficient killing of coagulase-positive Staphylococcus aureus cells in the mononuclear phagocytes of rabbits is shown to require heat-labile components of serum. The effect of serum in promoting phagocytosis and intracellular killing may be exhibited either by presensitization of the staphylococcal cells before contact with leukocytes or by the presence of serum in the phagocytic system. Under any conditions studied the rate of intracellular killing of S. aureus is very slow.
沙耶加尼，迈赫迪·G.（美国宾夕法尼亚州费城退伍军人管理局医院），以及斯图尔特·马德。血清在兔单核细胞内杀灭葡萄球菌中的作用。《细菌学杂志》91:1393 - 1398。1966年。——尽管在兔单核细胞中，加热的正常血清甚至用汉克斯溶液洗涤三次的单核细胞以及未接触血清的葡萄球菌都能发生一定程度的细胞内杀灭，但研究表明，兔单核吞噬细胞中有效杀灭凝固酶阳性金黄色葡萄球菌细胞需要血清中的热不稳定成分。血清促进吞噬作用和细胞内杀灭的作用，既可以通过在葡萄球菌细胞与白细胞接触前进行预致敏来体现，也可以通过吞噬系统中存在血清来体现。在所研究的任何条件下，金黄色葡萄球菌的细胞内杀灭速率都非常缓慢。
Zotero 插件