Nemo G J, Cutchins E C
J Bacteriol. 1966 Feb;91(2):798-802. doi: 10.1128/jb.91.2.798-802.1966.
Nemo, George J. (The Catholic University of America, Washington, D.C.), and Ernest C. Cutchins. Effect of visible light on canine distemper virus. J. Bacteriol. 91:798-802. 1966.-Canine distemper virus (CDV) was inactivated by visible light. The virus was light-sensitive in fluid suspension (in vitro) as well as during intracellular replication (in vivo). The addition of calf serum or glutathione reduced the extent of inactivation. CDV was less sensitive when suspended in distilled water or in the amino acid or Earle's salts components of the minimal essential medium of Eagle than when suspended in the vitamin component of the minimal essential medium of Eagle or in riboflavine (0.1 mg per liter). These findings indicate that, whereas some ingredient of the medium may enhance light sensitivity, its presence is not necessary for light inactivation of CDV. It is proposed that some substance derived from the host cell and intimately associated with the virus particle serves to render CDV light-sensitive.
内莫，乔治·J.（美国天主教大学，华盛顿特区），以及欧内斯特·C. 卡钦斯。可见光对犬瘟热病毒的影响。《细菌学杂志》91:798 - 802。1966年。——犬瘟热病毒（CDV）可被可见光灭活。该病毒在液体悬浮液中（体外）以及细胞内复制过程中（体内）对光敏感。添加小牛血清或谷胱甘肽可降低灭活程度。当CDV悬浮于蒸馏水中、伊格尔最低限度基本培养基的氨基酸或Earle氏盐成分中时，其敏感性低于悬浮于伊格尔最低限度基本培养基的维生素成分中或核黄素（每升0.1毫克）时。这些发现表明，尽管培养基中的某些成分可能增强光敏感性，但对于CDV的光灭活而言，其存在并非必要条件。有人提出，源自宿主细胞且与病毒颗粒紧密相关的某种物质致使CDV对光敏感。
