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Uptake of 5-hydroxytryptamine by isolated platelets in childhood schizophrenia and autism.

作者信息

Siva Sankar D V

出版信息

Neuropsychobiology. 1977;3(4):234-9. doi: 10.1159/000117608.

DOI:10.1159/000117608
PMID:593539
Abstract

Previous work indicated a platelet abnormality in the in vitro accumulation of serotonin in childhood schizophrenia, especially infantile autism. The present report validates this further in cases of infantile autism and shows that the abnormality seems to be due to the platelets. The defect is apparently associated with the platelet and not the plasma.

摘要

相似文献

1
Uptake of 5-hydroxytryptamine by isolated platelets in childhood schizophrenia and autism.
Neuropsychobiology. 1977;3(4):234-9. doi: 10.1159/000117608.
2
Biochemistry and schizophrenia III. A review of childhood psychosis.生物化学与精神分裂症III. 儿童期精神病综述
Schizophr Bull. 1975 Spring(12):18-32. doi: 10.1093/schbul/1.12.18.
3
Abnormalities in platelet 5-hydroxytryptamine efflux in patients with infantile autism.
Nature. 1970 Apr 25;226(5243):371-2. doi: 10.1038/226371a0.
4
CHILDHOOD PSYCHOSIS.儿童期精神病
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5
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Encephale. 1989 Mar-Apr;15(2):255-62.
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7
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The human platelet. A diagnostic and research tool for the study of biogenic amines in psychiatric and neurologic disorders.人类血小板。一种用于研究精神和神经疾病中生物胺的诊断及研究工具。
Arch Gen Psychiatry. 1977 May;34(5):509-16. doi: 10.1001/archpsyc.1977.01770170019001.
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[Metabolism of serotonin in autism in children].[儿童自闭症中血清素的代谢]
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Uptake and loss of 14 C-dopamine by platelets from children with infantile autism.
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引用本文的文献

1
Modeling rare gene variation to gain insight into the oldest biomarker in autism: construction of the serotonin transporter Gly56Ala knock-in mouse.对罕见基因突变进行建模以深入了解自闭症最早的生物标志物：构建血清素转运蛋白 Gly56Ala 敲入小鼠。
J Neurodev Disord. 2009 Jun;1(2):158-71. doi: 10.1007/s11689-009-9020-0.
2
Kinetics of 3H-serotonin uptake by platelets in infantile autism and developmental language disorder (including five pairs of twins).婴儿自闭症和发育性语言障碍（包括五对双胞胎）中血小板对3H-血清素摄取的动力学
J Autism Dev Disord. 1986 Mar;16(1):69-76. doi: 10.1007/BF01531579.
3
Platelet [3H]imipramine binding in autism and schizophrenia.
自闭症和精神分裂症中血小板[3H]丙咪嗪结合情况
Psychopharmacology (Berl). 1987;91(1):101-3. doi: 10.1007/BF00690935.
4
Plasma levels of folates, riboflavin, vitamin B6, and ascorbate in severely disturbed children.严重精神障碍儿童的血浆叶酸、核黄素、维生素B6和抗坏血酸水平。
J Autism Dev Disord. 1979 Mar;9(1):73-82. doi: 10.1007/BF01531294.