新生儿脑膜炎
Neonatal meningitis.
作者信息
Goldacre M J
出版信息
Postgrad Med J. 1977 Oct;53(624):607-9. doi: 10.1136/pgmj.53.624.607.
Some of the main features of neonatal meningitis, studied in a defined population of infants, are reviewed. The incidence rate was twenty-six cases per 100 000 live-births. The case fatality rate was 43%. Gram-negative intestinal bacilli were the commonest infecting organisms. Streptococci accounted for an important minority of cases. It is stressed that neonatal meningitis usually presents as a non-specific illness, without the clinical signs of meningitis which are familiar in older patients. Twenty-three of the seventy-six infants in this study (30%) weighed 2500 g or less at birth. Another eight infants were born to mothers whose membranes had been ruptured for 24 hr or more.
本文回顾了在特定婴儿群体中研究的新生儿脑膜炎的一些主要特征。发病率为每10万例活产中有26例。病死率为43%。革兰氏阴性肠道杆菌是最常见的感染病原体。链球菌占病例的相当比例。需要强调的是，新生儿脑膜炎通常表现为非特异性疾病，没有年长患者常见的脑膜炎临床体征。本研究中的76名婴儿中有23名（30%）出生时体重在2500克或以下。另外8名婴儿的母亲胎膜破裂时间达24小时或更长。
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