Frolova I A, Oleneva V A, Paramonova E G, Volkova I S, Sirota I I
Vopr Med Khim. 1977 Nov-Dec(6):797-803.
Excretion of catecholamines and DOPA was impaired in patients with metabolic-alimentary obesity, with ischemic disease of heart, with atherosclerosis and excessive weight. Distinct decrease in content of adrenaline, noradrenaline and DOPA was observed in patients with obesity; the phenomenon was less pronounced in ischemic disease of heart, mainly in aged patients. Correlation was found between the rate of excretion of catecholamines and DOPA and the extent of hyperlipidemia. Dietetics did not normalize completely the impairments studied. Additional administration of pyridoxine caused a favorable effect.
患有代谢性营养性肥胖、缺血性心脏病、动脉粥样硬化和超重的患者儿茶酚胺和多巴的排泄受损。在肥胖患者中观察到肾上腺素、去甲肾上腺素和多巴含量明显降低；这种现象在缺血性心脏病患者中不太明显，主要在老年患者中。发现儿茶酚胺和多巴的排泄率与高脂血症程度之间存在相关性。饮食疗法并未完全使所研究的损伤恢复正常。额外给予吡哆醇产生了良好效果。
