Hunt K J, Valentine M D, Sobotka A K, Lichtenstein L M
Ann Intern Med. 1976 Jul;85(1):56-9. doi: 10.7326/0003-4819-85-1-56.
SKin testing was done on 30 patients with a history of anaphylactic reactions after a Hymenoptera sting and on 30 control subjects. The patients all had positive basophilhistamine release to one or more venoms on challenge with the specific venoms used for skin testing (honey bee, yellow jacket, white-faced hornet, yellow hornet, and Polistes). At 0.1 mug of venom/ml and at 1.0 mug of venom/ml, 75% and 100%, respectively, of the sensitive patients had a positive skin test. There was a significant (P less than 0.001) correlation between skin test and histamine release results. Of the 150 skin tests in control patients, only 1 was positive. Venom skin tests provide, for the first time, a simple, readily available technique to accurately diagnose allergy to stinging insects.
对30例有膜翅目昆虫蜇伤后过敏反应病史的患者及30例对照者进行了皮肤试验。所有患者在用用于皮肤试验的特定毒液（蜜蜂、黄胡蜂、白脸大黄蜂、黄大黄蜂和长脚胡蜂）激发时，对一种或多种毒液的嗜碱性粒细胞组胺释放均呈阳性。在毒液浓度为0.1μg/ml和1.0μg/ml时，分别有75%和100%的敏感患者皮肤试验呈阳性。皮肤试验结果与组胺释放结果之间存在显著相关性（P<0.001）。在对照患者的150次皮肤试验中，只有1次呈阳性。毒液皮肤试验首次提供了一种简单、易于获得的技术，用于准确诊断对蜇人昆虫的过敏。
