Roth J, Mährlein W
Z Erkr Atmungsorgane. 1977;148(3):292-5.
In 432 patients examinations of bronchial reactivity with the acetylcholin test (3 min. inhalation of a 0.1% acetylcholine solution) were carried out with testing FEV1 immediately, 5 min. and 10 min. after stopping inhalation. It could be shown that the extent of bronchial hyperreactivity can be found by a single determination after acetylcholine provocation. It is proposed to use this one-step method for routine examinations and to measure FEV1 five min. after stopping inhalation. For clinical evaluation the intensity of bronchial reaction has also to be considered and estimated.
对432例患者进行了乙酰胆碱试验以检测支气管反应性（吸入0.1%乙酰胆碱溶液3分钟），在停止吸入后立即、5分钟和10分钟时检测第一秒用力呼气容积（FEV1）。结果表明，乙酰胆碱激发后单次测定即可发现支气管高反应性的程度。建议将这种一步法用于常规检查，并在停止吸入后5分钟测量FEV1。对于临床评估，还必须考虑并评估支气管反应的强度。
