Balish E, Svihla G
J Bacteriol. 1966 Dec;92(6):1812-20. doi: 10.1128/jb.92.6.1812-1820.1966.
Balish, Edward (Argonne National Laboratory, Argonne, Ill.), and George Svihla. Ultraviolet microscopy of Candida albicans. J. Bacteriol. 92:1812-1820. 1966.-Yeast and mycelial strains of Candida albicans were grown in medium supplemented with sulfur amino acids in an effort to determine factors that control the morphology and pathogenicity of the organism. Ultraviolet microscopy revealed a greater concentration of S-adenosylmethionine in the vacuoles of the mycelial phase than in those of yeast phases. Supplementation with amino acids greatly increased the concentration of S-adenosylmethionine in the mycelial phase, and made these cells more sensitive to the lytic action of snail gut enzymes than two yeast phase strains. This indicates a difference in cell wall structure that may be related to the pathogenicity of the mycelial phase.
巴利什，爱德华（伊利诺伊州阿贡国家实验室，阿贡）和乔治·斯维赫拉。白色念珠菌的紫外显微镜观察。《细菌学杂志》92:1812 - 1820。1966年。——为了确定控制白色念珠菌形态和致病性的因素，将白色念珠菌的酵母型和菌丝型菌株在添加了含硫氨基酸的培养基中培养。紫外显微镜观察显示，菌丝相液泡中S - 腺苷甲硫氨酸的浓度高于酵母相液泡中的浓度。添加氨基酸极大地增加了菌丝相中S - 腺苷甲硫氨酸的浓度，并且使这些细胞比两株酵母相菌株对蜗牛肠道酶的裂解作用更敏感。这表明细胞壁结构存在差异，这可能与菌丝相的致病性有关。
