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内在神经系统作用下胃慢电位频率的调节

Modulation of the slow potentials frequency of the stomach under the effect of the intrinsic nervous system.

作者信息

Atanassova E

出版信息

Acta Physiol Pharmacol Bulg. 1977;3(2):39-46.

PMID:596172
Abstract

Chronic and in situ experiments on dogs have been carried out involving stomach transection at the level of incisura angularis. The electrical acivity of the muscle wall of the two stomach segments was recorded by silver bipolar ball-shaped electrodes. Two electrodes for myogenic stimulation were implanted in the distal segment. Transection caused dissociation of the slow potentials rhythm in both stomach segments: slow potentials frequency in the distal segment is considerably reduced. Infusion of cholino- and adreno-mimetics in the artery supplying the distal segment causes increase of the frequency of the slow potentials in the distal segment to reach the frequency of the proximal segment. Bocking of the intrinsic nervous system eliminates these responses. On the background myogenic stimulation induces increased frequency of the rhythm in the distal segment. It is concluded that the intrinsic nervous system plays a role in maintaining slow potentials frequency in the stomach at a higher level than the level characteristic of this stomach segment.

摘要

已在犬身上进行了慢性和原位实验,包括在胃角切迹水平进行胃横断术。用双极球形银电极记录两个胃段肌壁的电活动。在远端段植入两个用于肌源性刺激的电极。横断术导致两个胃段的慢电位节律分离:远端段的慢电位频率显著降低。向供应远端段的动脉内注入拟胆碱药和拟肾上腺素药可使远端段慢电位频率增加,达到近端段的频率。阻断内在神经系统可消除这些反应。在肌源性刺激的背景下,可诱导远端段节律频率增加。得出的结论是,内在神经系统在将胃中慢电位频率维持在高于该胃段特征水平方面发挥作用。

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