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内在神经系统影响下胃和小肠肌电复合体的变化。

Changes in the myoelectric complex of the stomach and the small intestine under the influence of the intrinsic nervous system.

作者信息

Atanassova E, Kortezova N, Lolova I, Petrov I

出版信息

Acta Physiol Pharmacol Bulg. 1980;6(3):11-8.

PMID:6792862
Abstract

Chronic experiments have been carried out on dogs with implanted silver bipolar ball-shaped electrodes on the muscle wall of the stomach and of the duodenum after transthoracic truncus vagotomy. The appearance of incoordination in the rhythm of the slow potentials of the corpus and antrum is followed by an increase in the spike activity of the stomach and duodenum. The percentage of the spike activity increases, the active periods of the myoelectric complex become longer, with a decrease and even obliteration of the quiescent periods. These changes are most pronounced during the second post-vagotomy month, after which the spike activity gradually decreases and quiescent periods appear again. Nevertheless, at the end of the 6th month after the vagotomy, the spike activity has higher values than before the vagotomy. Chemical sympathectomy with 6-OHDA results in 100 per cent spike activity of the stomach and duodenum and complete absence of quiescent periods. It is concluded that the intrinsic nervous system is capable of organizing the phases of the myoelectric complex in the cases of absence of influence of the extrinsic nervous system.

摘要

在经胸切断迷走神经干后,对狗进行了慢性实验,在胃和十二指肠的肌壁上植入了银质双极球形电极。胃体和胃窦慢电位节律出现不协调后,胃和十二指肠的锋电位活动增加。锋电位活动的百分比增加,肌电复合波的活动期变长,静息期减少甚至消失。这些变化在迷走神经切断术后的第二个月最为明显,之后锋电位活动逐渐减少,静息期再次出现。然而,在迷走神经切断术后6个月末,锋电位活动的值高于迷走神经切断术前。用6-羟基多巴胺进行化学交感神经切除术导致胃和十二指肠100%的锋电位活动,且完全没有静息期。得出的结论是,在没有外在神经系统影响的情况下,内在神经系统能够组织肌电复合波的各阶段。

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