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Chemical structure and function of the active center of acetylcholinesterase.

作者信息

Krupka R M

出版信息

Biochemistry. 1966 Jun;5(6):1988-97. doi: 10.1021/bi00870a029.

DOI:10.1021/bi00870a029
PMID:5963443
Abstract
摘要

相似文献

1
Chemical structure and function of the active center of acetylcholinesterase.乙酰胆碱酯酶活性中心的化学结构与功能
Biochemistry. 1966 Jun;5(6):1988-97. doi: 10.1021/bi00870a029.
2
ACETYLCHOLINESTERASE: TRIMETHYLAMMONIUM-ION INHIBITION OF DEACETYLATION.乙酰胆碱酯酶：三甲铵离子对脱乙酰作用的抑制
Biochemistry. 1964 Nov;3:1749-54. doi: 10.1021/bi00899a029.
3
The acceleration of acetylcholinesterase activity at low ionic strength by organic and inorganic cations.
Mol Pharmacol. 1968 Mar;4(2):181-6.
4
The acceleration of the acetylcholinesterase catalyzed hydrolysis of acetyl fluoride.
Biochem Biophys Res Commun. 1967 Jul 21;28(2):263-9. doi: 10.1016/0006-291x(67)90439-1.
5
Hydrolysis of neutral substrates by acetylcholinesterase.乙酰胆碱酯酶对中性底物的水解作用。
Biochemistry. 1966 Jun;5(6):1983-8. doi: 10.1021/bi00870a028.
6
ARE IDENTICAL CATALYTIC GROUPS INVOLVED IN THE ACETYLATION AND DEACETYLATION STEPS OF ACETYLCHOLINESTERASE REACTIONS?参与乙酰胆碱酯酶反应的乙酰化和去乙酰化步骤的催化基团是否相同？
Biochem Biophys Res Commun. 1965 May 3;19:531-7. doi: 10.1016/0006-291x(65)90158-0.
7
Kinetic studies on the mechanism of insect acetylcholinesterase.
Biochemistry. 1970 Nov 24;9(24):4665-72. doi: 10.1021/bi00826a008.
8
ACETYLCHOLINESTERASE.乙酰胆碱酯酶
Can J Biochem. 1964 May;42:677-93. doi: 10.1139/o64-082.
9
A CORRELATION BETWEEN THE BIOLOGICAL ACTIVITY OF ALKYLTRIMETHYLAMMONIUM IONS AND THEIR MODE OF INTERACTION WITH ACETYLCHOLINESTERASE.烷基三甲基铵离子的生物活性与其与乙酰胆碱酯酶的相互作用模式之间的相关性
J Am Chem Soc. 1965 May 20;87:2283-5. doi: 10.1021/ja01088a033.
10
ACCELERATION OF THE RATE OF REACTION OF DIMETHYLCARBAMYL FLUORIDE AND ACETYLCHOLINESTERASE BY SUBSTITUTED AMMONIUM IONS.取代铵离子对二甲基氨甲酰氟与乙酰胆碱酯酶反应速率的加速作用。
J Biol Chem. 1963 Oct;238:3432-5.

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1
Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.解析甲磺酸酯与乙酰胆碱酯酶加合物的形成、机制和演变：对易受亲核试剂组合重新激活的类似老化失活复合物的深入了解。
Protein Sci. 2024 May;33(5):e4977. doi: 10.1002/pro.4977.
2
Rapid Mechanistic Evaluation and Parameter Estimation of Putative Inhibitors in a Single-Step Progress-Curve Analysis: The Case of Horse Butyrylcholinesterase.在单步进程曲线分析中快速评估和参数估计潜在抑制剂的机制：以马丁酰胆碱酯酶为例。
Molecules. 2017 Jul 26;22(8):1248. doi: 10.3390/molecules22081248.
3
Acetylcholine and its thiolester and selenolester analogs: conformation, electron distribution, and biological activity.
乙酰胆碱及其硫酯和硒酯类似物：构象、电子分布和生物活性。
Proc Natl Acad Sci U S A. 1969 Aug;63(4):1253-60. doi: 10.1073/pnas.63.4.1253.
4
Survey of chemical and related weapons of war.
Naturwissenschaften. 1973 Apr;60(4):177-83. doi: 10.1007/BF00599427.
5
[Concepts for the synthesis of new biologically active substances].[新型生物活性物质的合成概念]
Naturwissenschaften. 1979 Apr;66(4):173-81. doi: 10.1007/BF00366017.
6
Catalysis by acetylcholinesterase: evidence that the rate-limiting step for acylation with certain substrates precedes general acid-base catalysis.乙酰胆碱酯酶的催化作用：有证据表明，与某些底物进行酰化反应的限速步骤先于一般酸碱催化。
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3834-8. doi: 10.1073/pnas.72.10.3834.