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人粪便中三取代胆烷酸的表征

Characterization of trisubstituted cholanoic acids in human feces.

作者信息

Eneroth P, Gordon B, Sjövall J

出版信息

J Lipid Res. 1966 Jul;7(4):524-30.

PMID:5965294
Abstract

The trisubstituted cholanoic acids in human feces have been studied by gas chromatography-mass spectrometry. The following bile acids have been identified: 3 Beta,7alpha,12alpha-trihydroxy-, 3 Beta,7 Beta,12alpha-trihydroxy-, 3alpha,7alpha-dihydroxy-12-keto-5 Beta-cholanoic acids and 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholanoic acid. The presence in human feces of 3alpha,7alpha,12alpha-trihydroxy-, 3alpha,7,12alpha-trihydroxy-, and 3alpha,12alpha-dihydroxy-7-keto-5 Beta-cholanoic acids has been confirmed. The composition of bile acids in human feces is summarized and possible metabolic interrelationships suggested.

摘要

已通过气相色谱-质谱联用技术对人类粪便中的三取代胆烷酸进行了研究。已鉴定出以下胆汁酸：3β,7α,12α-三羟基、3β,7β,12α-三羟基、3α,7α-二羟基-12-酮-5β-胆烷酸和3α,7α,12α-三羟基-5α-胆烷酸。已证实人类粪便中存在3α,7α,12α-三羟基、3α,7,12α-三羟基和3α,12α-二羟基-7-酮-5β-胆烷酸。总结了人类粪便中胆汁酸的组成，并提出了可能的代谢相互关系。

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引用本文的文献

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Diurnal changes in serum unconjugated bile acids in normal man.正常男性血清非结合胆汁酸的昼夜变化
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