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[谢尔曼丙酸杆菌对抗菌制剂的敏感性及维生素B12的合成]

[Sensitivity of Sherman's propionic acid bacilli to antibacterial preparations and vitamin B12 synthesis].

作者信息

Sidorchuk I I

出版信息

Antibiotiki. 1977 Nov;22(11):1015-7.

PMID:596839
Abstract

Sherman propionic acid bacilli were sensitive to benzylpenicillin, ampicillin, ceporin, tetracyclines, oleandomycin, oletetrin, tetraolean, sigmamycin, levomycetin and furadonine. Methicillin, oxacillin, monomycin, kanamycin, polymyxin and furazolidone had an insignificant effect on the above organism. The subbacteriostatic concentrations of methicillin, oxacillin, streptomycin, monomycin, kanamycin, neomycin, tetraolean, sigmamycin, polymyxin M and ristomycin increased the biosynthesis of vitamin B12 by Sherman propionic acid bacilli, while benzylpenicillin, ampicillin, tetracyclines, oleandomycin, oletetrin, levomycetin and furadonine in the subbacteriostatic concentrations inhibited this process.

摘要

谢尔曼丙酸杆菌对苄青霉素、氨苄青霉素、头孢菌素、四环素、竹桃霉素、竹桃菌素、四烯大环内酯、西曲霉素、氯霉素和呋喃妥因敏感。甲氧西林、苯唑西林、莫能菌素、卡那霉素、多粘菌素和呋喃唑酮对上述微生物影响不显著。甲氧西林、苯唑西林、链霉素、莫能菌素、卡那霉素、新霉素、四烯大环内酯、西曲霉素、多粘菌素M和瑞斯托菌素的亚抑菌浓度可增加谢尔曼丙酸杆菌维生素B12的生物合成,而苄青霉素、氨苄青霉素、四环素、竹桃霉素、竹桃菌素、氯霉素和呋喃妥因的亚抑菌浓度则抑制这一过程。

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