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[1975 - 1979年沙门氏菌对抗生素的敏感性及其在鼠伤寒沙门氏菌中的特征]

[Salmonellal sensitivity to antibiotics in 1975-1979 and its characteristics in S. typhimurium].

作者信息

Garanin B A

出版信息

Antibiotiki. 1981 Apr;26(4):271-4.

PMID:7016022
Abstract

Sensitivity of 314 Salmonella strains of 16 serotypes of the main groups ABCDE isolated from patients with salmonellosis in 1975-1979 was studied with the method of standard paper disks with respect to levomycetin, streptomycin, tetracycline, monomycin, erythromycin, oleandomycin and in a part of the cultures to kanamycin, ristomycin, ampicillin, carbenicillin and polymyxin. 78 per cent of the strains fell within S. typhimurium. It was found that S. typhimurium had higher resistance levels to the above antibiotics and the so called "hospital" strains of the pathogens were mainly resistant simultaneously to 4-12 antibiotics. The Salmonella strains of the other serotypes isolated mainly in 1975-1977 preserved sufficient sensitivity to the antibiotics used for the most prolonged periods and most widely in therapy.

摘要

采用标准纸片法,对1975年至1979年从沙门氏菌病患者中分离出的主要ABCDE组16种血清型的314株沙门氏菌,就氯霉素、链霉素、四环素、土霉素、红霉素、竹桃霉素进行了敏感性研究,部分培养物还对卡那霉素、瑞斯托霉素、氨苄青霉素、羧苄青霉素和多粘菌素进行了研究。78%的菌株属于鼠伤寒沙门氏菌。发现鼠伤寒沙门氏菌对上述抗生素的耐药水平较高,所谓病原体的“医院”菌株主要同时对4至12种抗生素耐药。主要在1975年至1977年分离出的其他血清型沙门氏菌菌株,对治疗中使用时间最长、范围最广的抗生素仍保持足够的敏感性。

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