Rathová V, Kocisková D, Borecký L
Arch Immunol Ther Exp (Warsz). 1977;25(5):707-13.
Further data were obtained in support of the finding that the levels of interferon and complement show a negative correlation after induction of interferon in vivo. Experiments with selective chelating agents showed that the activation of complement occurs by the by-pass mechanism. Preliminary results indicate that interferon itself can reduce the level of complement in vivo. Experiments are underway to verify in rats the results obtained in mice.
在体内诱导干扰素后,干扰素水平与补体水平呈负相关。使用选择性螯合剂的实验表明,补体的激活是通过旁路机制发生的。初步结果表明,干扰素本身可降低体内补体水平。正在进行实验以在大鼠中验证在小鼠中获得的结果。