Sperling D R, Beran A V
Ann Thorac Surg. 1976 Feb;21(2):151-7. doi: 10.1016/s0003-4975(10)64279-8.
In 12 rabbits hypothermia and rewarming were induced with temperature-controlled circulating peritoneal dialysis in combination with temperature-controlled hypoxic and hypercapnic gas mixtures. The average cooling time necessary for the esophageal temperature to decrease from 37.7 degrees +/- 0.7 to 20.6 degrees +/- 1.0 degrees C was 81 +/- 34 minutes with a range of 41 to 150 minutes. The average warming time for esophageal temperature to increase from 20.6 degrees +/- 1.0 degrees C to 35.2 degrees +/- 1.8 degrees C was 90 +/- 35 minutes. Time of cooling was related to the proportions of inspired carbon dioxide and oxygen. In contrast to surface and bypass methods, esophageal and muscular temperatures agreed very closely, suggesting an absence of regional temperature gradients.
对12只兔子进行了降温及复温处理，采用温度控制的循环腹膜透析并结合温度控制的低氧和高碳酸血症混合气体。食管温度从37.7度±0.7度降至20.6度±1.0度所需的平均降温时间为81±34分钟，范围为41至150分钟。食管温度从20.6度±1.0度升至35.2度±1.8度的平均复温时间为90±35分钟。降温时间与吸入二氧化碳和氧气的比例有关。与体表和体外循环方法不同，食管温度和肌肉温度非常接近，表明不存在局部温度梯度。
