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Acute effects of insulin on glycerol phosphate acyl transferase activity, ketogenesis and serum free fatty acid concentration in perfused rat liver.

作者信息

Bates E J, Topping D L, Sooranna S P, Saggerson D, Mayes P A

出版信息

FEBS Lett. 1977 Dec 15;84(2):225-8. doi: 10.1016/0014-5793(77)80693-5.

DOI:10.1016/0014-5793(77)80693-5
PMID:598501
Abstract
摘要

相似文献

1
Acute effects of insulin on glycerol phosphate acyl transferase activity, ketogenesis and serum free fatty acid concentration in perfused rat liver.胰岛素对灌注大鼠肝脏中磷酸甘油酰基转移酶活性、生酮作用及血清游离脂肪酸浓度的急性影响。
FEBS Lett. 1977 Dec 15;84(2):225-8. doi: 10.1016/0014-5793(77)80693-5.
2
Glycerophosphate acetyltransferase activity in perfused liver of normal and hyperlipemic rats: glucagon effect.正常和高脂血症大鼠灌注肝脏中甘油磷酸乙酰转移酶活性：胰高血糖素的作用
Acta Diabetol Lat. 1981 Oct-Dec;18(4):357-63. doi: 10.1007/BF02042820.
3
Studies of the effect of adrenaline on glycerol phosphate acyltransferase activity in rat adipocytes.
FEBS Lett. 1978 Jun 1;90(1):141-4. doi: 10.1016/0014-5793(78)80316-0.
4
Regulation of hepatic fatty acid metabolism. The activities of mitochondrial and microsomal acyl-CoA:sn-glycerol 3-phosphate O-acyltransferase and the concentrations of malonyl-CoA, non-esterified and esterified carnitine, glycerol 3-phosphate, ketone bodies and long-chain acyl-CoA esters in livers of fed or starved pregnant, lactating and weaned rats.肝脏脂肪酸代谢的调节。喂食或饥饿的怀孕、哺乳和断奶大鼠肝脏中线粒体和微粒体酰基辅酶A：sn-甘油3-磷酸O-酰基转移酶的活性以及丙二酰辅酶A、非酯化和酯化肉碱、甘油3-磷酸、酮体和长链酰基辅酶A酯的浓度。
Biochem J. 1981 Jul 15;198(1):75-83. doi: 10.1042/bj1980075.
5
Biosynthesis of glycerolipids by hepatoma and liver microsomes. I. Fatty acyl-CoA ligase and acyl-CoA:sn-glycerol-3-phosphate acyltransferase.肝癌细胞微粒体和肝脏微粒体中甘油脂质的生物合成。I. 脂肪酰辅酶A连接酶和酰基辅酶A：sn-甘油-3-磷酸酰基转移酶
Biochim Biophys Acta. 1987 Feb 14;917(2):247-57. doi: 10.1016/0005-2760(87)90129-9.
6
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment.大鼠肝脏线粒体和微粒体组分中甘油磷酸酰基转移酶和磷酸二羟丙酮酰基转移酶活性的研究。在实质细胞和非实质细胞中的相对分布、N-乙基马来酰亚胺的影响、棕榈酰辅酶A浓度、饥饿、肾上腺切除术及抗胰岛素血清处理的影响
Biochem J. 1979 Sep 15;182(3):751-62. doi: 10.1042/bj1820751.
7
A trypsin-sensitive, heat-labile, N-ethylmaleimide-sensitive factor in adipocyte post-microsomal supernatant which affects the assay of adipocyte glycerol phosphate acyltransferase activities.脂肪细胞微粒体后上清液中一种对胰蛋白酶敏感、对热不稳定、对N - 乙基马来酰亚胺敏感的因子，它会影响脂肪细胞甘油磷酸酰基转移酶活性的测定。
Biochem J. 1983 Jul 15;214(1):247-55. doi: 10.1042/bj2140247.
8
Sex differences in long chain fatty acid utilization and fatty acid binding protein concentration in rat liver.大鼠肝脏中长链脂肪酸利用及脂肪酸结合蛋白浓度的性别差异。
J Clin Invest. 1979 Jul;64(1):172-81. doi: 10.1172/JCI109437.
9
Regulation by noradrenaline of the mitochondrial and microsomal forms of glycerol phosphate acyltransferase in rat adipocytes.去甲肾上腺素对大鼠脂肪细胞中线粒体和微粒体形式的甘油磷酸酰基转移酶的调节作用。
Biochem J. 1983 Jul 15;214(1):235-46. doi: 10.1042/bj2140235.
10
Effects of 2[5(4-chlorophenyl)pentyl]oxirane-2-carboxylate on lipoprotein lipase, adipose tissue lipolysis and glycerol phosphate acyltransferase in rats.2-[5-(4-氯苯基)戊基]环氧乙烷-2-羧酸酯对大鼠脂蛋白脂肪酶、脂肪组织脂解作用及甘油磷酸酰基转移酶的影响
Biochem Pharmacol. 1987 Mar 15;36(6):971-2. doi: 10.1016/0006-2952(87)90193-6.

引用本文的文献

1
Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK.芒果苷通过激活 AMPK 促进肝脏中游离脂肪酸的分解代谢来降低血浆游离脂肪酸。
PLoS One. 2012;7(1):e30782. doi: 10.1371/journal.pone.0030782. Epub 2012 Jan 23.
2
Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis.甘油-3-磷酸酰基转移酶：三酰甘油生物合成的限速酶。
Biochim Biophys Acta. 2009 Jun;1791(6):501-6. doi: 10.1016/j.bbalip.2008.10.010. Epub 2008 Nov 7.
3
The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function.
丙二酰辅酶A-长链酰基辅酶A轴在维持哺乳动物细胞功能中的作用
Biochem J. 1999 Nov 1;343 Pt 3(Pt 3):505-15.
4
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.AMP激活的蛋白激酶对肝脏和肌肉中三酰甘油的合成与脂肪酸氧化进行反向调节：证明sn-甘油-3-磷酸酰基转移酶是一个新靶点。
Biochem J. 1999 Mar 15;338 ( Pt 3)(Pt 3):783-91.
5
Role of insulin in hepatic fatty acid partitioning: emerging concepts.胰岛素在肝脏脂肪酸分配中的作用：新出现的概念
Biochem J. 1996 Feb 15;314 ( Pt 1)(Pt 1):1-14. doi: 10.1042/bj3140001.
6
Interactions between vasopressin and glucagon on ketogenesis and oleate metabolism in isolated hepatocytes from fed rats.血管升压素与胰高血糖素对喂食大鼠分离肝细胞中酮体生成和油酸代谢的相互作用。
Biochem J. 1980 Feb 15;186(2):621-4. doi: 10.1042/bj1860621.
7
Role of glycerol 3-phosphate and glycerophosphate acyltransferase in the nutritional control of hepatic triacylglycerol synthesis.3-磷酸甘油和甘油磷酸酰基转移酶在肝脏三酰甘油合成营养调控中的作用
Biochem J. 1982 Apr 15;204(1):247-56. doi: 10.1042/bj2040247.
8
Insulin and non-esterified fatty acids. Acute regulators of lipogenesis in perfused rat liver.胰岛素和非酯化脂肪酸。灌注大鼠肝脏中脂肪生成的急性调节因子。
Biochem J. 1982 May 15;204(2):433-9. doi: 10.1042/bj2040433.
9
Short-term regulation of hepatic triacylglycerol metabolism by insulin and glucagon.胰岛素和胰高血糖素对肝脏三酰甘油代谢的短期调节。
Vet Res Commun. 1982 May;5(3):223-36. doi: 10.1007/BF02214989.
10
Glycerophosphate acetyltransferase activity in perfused liver of normal and hyperlipemic rats: glucagon effect.正常和高脂血症大鼠灌注肝脏中甘油磷酸乙酰转移酶活性：胰高血糖素的作用
Acta Diabetol Lat. 1981 Oct-Dec;18(4):357-63. doi: 10.1007/BF02042820.