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对正常人肾脏可溶性抗原的免疫化学和酶学研究。

Immunochemical and enzymatic studies on the soluble antigens of normal human kidney.

作者信息

Dinh B L, Brassard A, Raghavan S R, Mardini A, Poirier L

出版信息

Nephron. 1976;17(2):104-20. doi: 10.1159/000180716.

DOI:10.1159/000180716
PMID:59906
Abstract

The antigenic composition of the soluble extract from normal human kidney was determined with the combined techniques of immunological absorption, immuno-diffusion and immunoelectrophoresis. The kidney extract contained at least eleven non-serum, tissue antigens; some of them were found in the extracts of other organs, but three were kidney-specific. None of the soluble tissue antigens from human kidney was characterized as a lipoprotein; however, three of them stained with the reagent for glycoproteins. Esterase activities were also demonstrated in four non-serum, renal antigens, one of which was present only in the kidney extract and absent in the other organs extracts.

摘要

采用免疫吸收、免疫扩散和免疫电泳相结合的技术,对正常人肾脏可溶性提取物的抗原成分进行了测定。肾脏提取物至少含有11种非血清组织抗原;其中一些在其他器官的提取物中也有发现,但有3种是肾脏特异性的。人肾可溶性组织抗原均未被鉴定为脂蛋白;然而,其中3种能用糖蛋白试剂染色。在4种非血清肾抗原中也证实有酯酶活性,其中1种仅存在于肾脏提取物中,而在其他器官提取物中不存在。

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