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Evaluation of the non-randomness of protein compositions.

作者信息

Cornish-Bowden A, Marson A

出版信息

J Mol Evol. 1977 Dec 29;10(3):231-40. doi: 10.1007/BF01764598.

DOI:10.1007/BF01764598
PMID:599573
Abstract

A method is described for assessing the non-randomness of protein compositions, based on the chi-squared statistic for the differences between the observed numbers of residues of each type and the numbers expected for a random distribution of codons. The analysis indicates that changes in at least 30% of the residues in natural proteins are selected against.

摘要

相似文献

1
Evaluation of the non-randomness of protein compositions.
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引用本文的文献

1
Early assignments of the genetic code dependent upon protein structure.遗传密码的早期分配依赖于蛋白质结构。
Orig Life. 1980 Mar;10(1):3-14. doi: 10.1007/BF00928939.
2
The amino acid compositions of proteins are correlated with their molecular sizes.蛋白质的氨基酸组成与其分子大小相关。
Biochem J. 1983 Jul 1;213(1):271-4. doi: 10.1042/bj2130271.
3
An estimate on the effect of point mutation and natural selection on the rate of amino acid replacement in proteins.关于点突变和自然选择对蛋白质中氨基酸替换率影响的估计。

本文引用的文献

1
Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid.脱氧核糖核酸的酶促合成。VIII. 脱氧核糖核酸中相邻碱基序列的频率
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Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoalleles.由于中性和近中性等位基因的突变产生，有限种群中维持的遗传变异性。
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Evaluation of compositional nonrandomness in proteins.
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一种用于确定基因中密码子变异性的改进方法及其在进化中突变固定速率的应用。
Biochem Genet. 1970 Oct;4(5):579-93. doi: 10.1007/BF00486096.
4
Tables of critical values for examining compositional non-randomness in proteins and nucleic acids.
J Mol Evol. 1975 Mar 24;4(4):261-76. doi: 10.1007/BF01732531.
5
Compositional nonrandomness: a quantitatively conserved evolutionary invariant.
J Mol Evol. 1975 Oct 3;6(1):1-14. doi: 10.1007/BF01732670.
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Nucleotide sequence of bacteriophage phi X174 DNA.噬菌体φX174 DNA的核苷酸序列。
Nature. 1977 Feb 24;265(5596):687-95. doi: 10.1038/265687a0.
7
The molecular evolution of cytochrome c in eukaryotes.真核生物中细胞色素c的分子进化
J Mol Evol. 1976 Jun 23;8(1):13-40. doi: 10.1007/BF01738880.
8
Deviations from compositional randomness in eukaryotic and prokaryotic proteins: the hypothesis of selective-stochastic stability and a principle of charge conservation.
J Mol Evol. 1975 Mar 24;4(4):277-306. doi: 10.1007/BF01732532.