Grabauskas V I, Baubinene A V, Glazunov I S, Domarkene S B, Misiavichene I S
Kardiologiia. 1977 Nov;17(11):111-7.
A prospective study was conducted from March 1972 to November 1976 in a group of Kaunas male population ranging in age from 45 to 59 years. At the beginning of the study it consisted of 3,553 individuals. They were divided into groups of low, moderate, and high risk according to the presence of a risk factor (hypertension, hypercholesteremia, impaired glucose tolerance test) and a pathologic condition. The ratio of the total mortality rate per 1,000 of the population during the observation period in these groups was 1 : 2 : 3, while that of the mortality of ischemic heart disease was 1 : 3 : 5. The rate of out-patient coronary mortality and the occurrence of new cases with myocardial infraction according to their number registered in the groups of low, moderate, and high risk was 1 : 2 : 5. All the indices in the group of individuals who refused to take part in the study were close to those in the high risk group. The data obtained point to the possibility of defecting by means of preventive study individuals exposed to a greater or lesser risk of the development of ischemic heart disease and death, which makes it possible for the Public Health Service to concentrate attention of definite groups of the population so as to apply differentiated preventive measures.
1972年3月至1976年11月,对考纳斯一组年龄在45至59岁之间的男性人群进行了一项前瞻性研究。研究开始时,该组共有3553人。根据是否存在危险因素(高血压、高胆固醇血症、葡萄糖耐量试验受损)和病理状况,他们被分为低风险、中度风险和高风险组。在观察期内,这些组中每1000人的总死亡率之比为1:2:3,而缺血性心脏病的死亡率之比为1:3:5。根据低风险、中度风险和高风险组登记的门诊冠状动脉死亡率和心肌梗死新发病例数,其比例为1:2:5。拒绝参加研究的个体组中的所有指标均与高风险组中的指标相近。所获得的数据表明,通过预防性研究有可能发现处于缺血性心脏病和死亡发生风险或多或少的个体,这使得公共卫生服务机构能够将注意力集中在特定人群上,从而采取差异化的预防措施。