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肉芽肿性结肠炎:不仅仅是犬类疾病?一例成年猫的相关肉芽肿性结肠炎病例。

Granulomatous colitis: more than a canine disease? A case of -associated granulomatous colitis in an adult cat.

作者信息

Leal Rodolfo Oliveira, Simpson Kenny, Fine Mélanie, Husson Jean-Charles, Hernandez Juan

机构信息

Fregis Veterinary Health Centre, Arcueil, France.

College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

出版信息

JFMS Open Rep. 2017 Sep 19;3(2):2055116917731168. doi: 10.1177/2055116917731168. eCollection 2017 Jul-Dec.

Abstract

CASE SUMMARY

This report describes a 4-year-old cat with chronic intermittent haematochezia and faecal incontinence of 7 months' duration. Investigation revealed severe colonic multifocal mucosal ulcerations and infiltration of the mucosal lamina propria by large numbers of periodic acid-Schiff-positive macrophages. Fluorescence in situ hybridisation analysis of colonic biopsies revealed multifocal clusters of intracellular . Treatment with fluoroquinolones for 6 weeks led to a complete resolution of clinical signs.

RELEVANCE AND NOVEL INFORMATION

The findings reveal that mucosally invasive can also be associated with granulomatous colitis in cats and indicate the need for diagnostic testing of mucosal samples for and other infectious agents.

摘要

病例摘要

本报告描述了一只4岁的猫,患有持续7个月的慢性间歇性便血和大便失禁。检查发现严重的结肠多灶性黏膜溃疡,大量过碘酸雪夫染色阳性巨噬细胞浸润黏膜固有层。对结肠活检组织进行荧光原位杂交分析发现细胞内多灶性聚集。用氟喹诺酮治疗6周后临床症状完全缓解。

相关性和新信息

这些发现表明,黏膜侵袭性 也可能与猫的肉芽肿性结肠炎有关,并提示需要对黏膜样本进行 及其他感染因子的诊断检测。

需注意,原文中部分内容缺失关键信息,以上译文是基于现有完整部分进行的翻译。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9f/5607922/66ca53d32c3a/10.1177_2055116917731168-fig1.jpg

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