豚鼠的子宫扩张与黄体功能
Uterine distension and the function of the corpora lutea in the guinea-pig.
作者信息
Bland K P, Donovan B T
出版信息
J Physiol. 1966 Oct;186(3):503-15. doi: 10.1113/jphysiol.1966.sp008052.
Abstract
- The presence of two glass beads (7 x 3 mm) in each horn of the uterus was associated with a reduction of 3-4 days in the length of the oestrous cycle.2. Two beads inserted into each uterine horn between days 2 and 4 exerted a greater effect on the oestrous cycle than either one bead in each horn or four beads in one horn only. Two beads located in one horn failed to affect cycle length.3. Measurement of the volume of the corpora lutea showed that distension of the uterus induced a premature regression in the size of the luteal bodies.4. When glass beads were present in one uterine horn, early and unilateral regression of the corpora lutea in the ovary adjacent to the distended horn was observed. Regression of the corpora lutea in the opposite ovary proceeded normally.5. In view of the local effect of uterine distension and other information, it is concluded that each uterine horn can produce a luteolytic substance which is conveyed to the neighbouring ovary to act upon the corpora lutea.
摘要
子宫每个角部存在两颗玻璃珠（7×3毫米）会使发情周期长度缩短3 - 4天。
在第2至4天向每个子宫角插入两颗珠子对发情周期的影响比每个角插入一颗珠子或仅在一个角插入四颗珠子更大。位于一个角的两颗珠子未能影响周期长度。
黄体体积的测量表明，子宫扩张会导致黄体提前退化。
当一个子宫角存在玻璃珠时，观察到与扩张角相邻的卵巢中的黄体出现早期单侧退化。对侧卵巢中的黄体退化正常进行。
鉴于子宫扩张的局部效应及其他信息，得出结论：每个子宫角可产生一种溶黄体物质，该物质被输送至相邻卵巢作用于黄体。
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本文引用的文献
1
Further studies on the neurogenic control of the estrous cycle by uterine distention.关于子宫扩张对发情周期神经源性控制的进一步研究。
Endocrinology. 1955 Mar;56(3):225-31. doi: 10.1210/endo-56-3-225.
2
CORPUS LUTEUM CONTROL IN HYSTERECTOMIZED GUINEA-PIGS.
J Endocrinol. 1965 May;32:153-60. doi: 10.1677/joe.0.0320153.
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The effect of uterine distension on the oestrous cycle of the guinea-pig.子宫扩张对豚鼠发情周期的影响。
J Physiol. 1962 May;161(2):227-36. doi: 10.1113/jphysiol.1962.sp006883.
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Neurogenic effects of uterine distention on the estrous cycle of the ewe.子宫扩张对母羊发情周期的神经源性影响。
Endocrinology. 1953 Jul;53(1):1-11. doi: 10.1210/endo-53-1-1.
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Local control of luteal function by the uterus of the guinea-pig.豚鼠子宫对黄体功能的局部调节。
Nature. 1965 Aug 21;207(999):867-9. doi: 10.1038/207867a0.
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