Cromer J A, Hunter W L, Bennett P B
Undersea Biomed Res. 1977 Dec;4(4):403-8.
The modification of the development of the high pressure nervous syndrome (HPNS) has been demonstrated by varying the external environment (chamber temperature, compression rate) or the internal environment (core temperature, pharmacology, age). This study examined the effects of compression rate on the convulsion-threshold pressure and EEG activity in 68 adult male Wistar rats with chronically implanted electrodes. Restrained animals were individually compressed at a predetermined rate in helium-oxygen to a simulated depth of 4500 fsw (137 ATA), with colonic temperature maintained at normal levels. Six compression rates showed that convulsion-threshold pressure for euthermic rats did not significantly differ between any of the groups.
通过改变外部环境（舱室温度、加压速率）或内部环境（核心温度、药理学、年龄），已证实高压神经综合征（HPNS）的发展会发生改变。本研究检测了68只长期植入电极的成年雄性Wistar大鼠的加压速率对惊厥阈值压力和脑电图活动的影响。将受限动物在氦氧环境中以预定速率单独加压至模拟深度4500英尺海水（137个绝对大气压），同时将结肠温度维持在正常水平。六种加压速率显示，体温正常的大鼠的惊厥阈值压力在任何组之间均无显著差异。
