大鼠发育过程中肝脏脂肪酸氧化酶活性的变化
Changes in the activities of the enzymes of hepatic fatty acid oxidation during development of the rat.
作者信息
Foster P C, Bailey E
出版信息
Biochem J. 1976 Jan 15;154(1):49-56. doi: 10.1042/bj1540049.
Abstract
- Changes in the activities of several enzymes involved in mitochondrial fatty acid oxidation were measured in livers of developing rats between late foetal life and maturity. The enzymes studied are medium- and long-chain ATP-dependent acyl-CoA synthetases of the outer mitochondrial membrane and matrix, GTP-dependent acyl-CoA synthetase, carnitine acyltransferase, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, general 3-oxoacyl-CoA thiolase and acetoacetyl-CoA thiolase.
摘要
- 在发育中的大鼠从胎儿后期到成熟阶段的肝脏中，测量了几种参与线粒体脂肪酸氧化的酶的活性变化。所研究的酶包括线粒体外膜和基质中的中链和长链ATP依赖性酰基辅酶A合成酶、GTP依赖性酰基辅酶A合成酶、肉碱酰基转移酶、烯酰辅酶A水合酶、3-羟酰基辅酶A脱氢酶、通用的3-氧代酰基辅酶A硫解酶和乙酰乙酰辅酶A硫解酶。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
3
The action of thyroid hormones at the cell level.甲状腺激素在细胞水平的作用。
Biochem J. 1963 Mar;86(3):408-28. doi: 10.1042/bj0860408.
4
Tissue fractionation studies. 12. Intracellular distribution of some dehydrogenases, alkaline deoxyribonuclease and iron in rat-liver tissue.组织分级分离研究。12. 大鼠肝脏组织中某些脱氢酶、碱性脱氧核糖核酸酶和铁的细胞内分布。
Biochem J. 1959 Dec;73(4):623-8. doi: 10.1042/bj0730623.
5
Phosphoenolpyruvate carboxykinase and pyruvate carboxylase in developing rat liver.发育中大鼠肝脏中的磷酸烯醇式丙酮酸羧激酶和丙酮酸羧化酶
Biochem J. 1967 Sep;104(3):866-71. doi: 10.1042/bj1040866.
6
Long-chain acyl-CoA synthetase in rat liver. A new assay procedure for the enzyme, and studies on its intracellular localization.大鼠肝脏中的长链脂酰辅酶A合成酶。该酶的一种新检测方法及其细胞内定位研究。
Biochim Biophys Acta. 1967 Mar 15;132(2):492-502. doi: 10.1016/0005-2744(67)90167-2.
7
Removal of fatty acids from serum albumin by charcoal treatment.通过活性炭处理从血清白蛋白中去除脂肪酸。
J Biol Chem. 1967 Jan 25;242(2):173-81.
8
Acetoacetate formation by liver slices from adult and infant rats.成年和幼年大鼠肝脏切片生成乙酰乙酸的情况。
Biochem J. 1964 Oct;93(1):61-5. doi: 10.1042/bj0930061.
9
The effect of treatment of rats with pituitary growth hormone on the activities of some enzymes involved in fatty acid degradation and synthesis.用垂体生长激素治疗大鼠对参与脂肪酸降解和合成的某些酶活性的影响。
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10
Activity and intracellular distribution of enzymes of ketone-body metabolism in rat liver.大鼠肝脏中酮体代谢酶的活性及细胞内分布
Biochem J. 1968 Jul;108(3):353-61. doi: 10.1042/bj1080353.
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