Morton H E, Roberts R J
J Bacteriol. 1967 Feb;93(2):711-5. doi: 10.1128/jb.93.2.711-715.1967.
Mycoplasma strain 4330, one of the earliest strains of pleuropneumonia-like organisms to be isolated from man in the United States, has been found to resemble M. hominis type 1 by serological methods (the growth inhibition and latex agglutination tests). The results of earlier serological studies indicated a similarity between the Campo and 4330 strains which was not detected by use of the cultures currently available. Strain 4330 differs from strains of Mycoplasma recently isolated from man by producing acid from a variety of carbohydrates. This acquisition of biochemical properties may be the result of hundreds of transfers on artificial media during a period of more than a quarter of a century. Identification of the strain was deemed advisable, since two different cultures and a mixed culture existed under the designation "4330." The extraneous organisms were found to be closely related to M. laidlawii by their biological and serological properties.
支原体菌株4330是在美国最早从人类分离出的类胸膜肺炎微生物菌株之一，通过血清学方法（生长抑制和乳胶凝集试验）已发现它与1型人型支原体相似。早期血清学研究结果表明，Campo菌株和4330菌株之间存在相似性，但使用目前可得的培养物未检测到这种相似性。4330菌株与最近从人类分离出的支原体菌株不同，它能利用多种碳水化合物产酸。在超过四分之一个世纪的时间里，这种生化特性的获得可能是在人工培养基上进行数百次传代的结果。鉴于存在两种不同的培养物以及一种标记为“4330”的混合培养物，对该菌株进行鉴定被认为是可取的。通过生物学和血清学特性发现，这些外来微生物与莱氏无胆甾原体密切相关。
