对紫外线敏感的酵母突变体。
Mutants of yeast sensitive to ultraviolet light.
作者信息
Snow R
出版信息
J Bacteriol. 1967 Sep;94(3):571-5. doi: 10.1128/jb.94.3.571-575.1967.
Abstract
Six uvr mutants of Saccharomyces cerevisiae with hypersensitivity to ultraviolet (UV) light were isolated after mutagen treatment with ethylmethanesulfonate. UV sensitivity ranges from moderate to extreme, and four of the mutants are also sensitive to nitrous acid. Ranking in terms of UV sensitivity does not parallel ranking in terms of nitrous acid sensitivity. Homozygous diploid mutant strains are somewhat less sensitive than the corresponding haploids. All mutations are recessive. None of the mutants is sensitive to gamma rays, and each shows photoreactivation after UV radiation. Complementation tests and tetrad analysis indicate that each strain represents mutation in a different gene. Two of the uvr genes are linked, and two others are centromere-linked.
摘要
在用甲磺酸乙酯进行诱变处理后，分离出了六株对紫外线（UV）敏感的酿酒酵母uvr突变体。UV敏感性范围从中度到极度，其中四个突变体对亚硝酸也敏感。按UV敏感性排序与按亚硝酸敏感性排序并不平行。纯合二倍体突变菌株比相应的单倍体菌株敏感性略低。所有突变均为隐性。没有一个突变体对γ射线敏感，并且每个突变体在UV辐射后都表现出光复活现象。互补试验和四分体分析表明，每个菌株代表一个不同基因的突变。其中两个uvr基因是连锁的，另外两个与着丝粒连锁。
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