Goto S, Homma J Y, Mudd S
J Bacteriol. 1967 Sep;94(3):751-8. doi: 10.1128/jb.94.3.751-758.1967.
Micrographs are presented of antibodies in combination with flagella of Salmonella typhi and with a phage-bound pyocine Rmc, which is supposed to be the tail of a defective bacteriophage from Pseudomonas aeruginosa. The pyocine preparation seems to offer advantages for the study of antibody-antigen complexes. Under the conditions of our experiments, the surfaces of the antigenic structures are saturated with antibody layers approximately 95 A in thickness, i.e., slightly less than half the accepted lengths of 7S antibody molecules. Our interpretation is that the antibody is attached by combining sites at the ends of the molecules to form loops along the surface of the antigenic structures.
展示了抗体与伤寒沙门氏菌鞭毛以及与噬菌体结合的绿脓菌素Rmc相结合的显微照片，绿脓菌素Rmc被认为是来自铜绿假单胞菌的缺陷噬菌体的尾部。绿脓菌素制剂似乎为抗体 - 抗原复合物的研究提供了优势。在我们的实验条件下，抗原结构的表面被厚度约为95埃的抗体层饱和，即略小于公认的7S抗体分子长度的一半。我们的解释是，抗体通过分子末端的结合位点附着，沿着抗原结构的表面形成环。
