Burrows R, Spooner P R, Goodridge D
Dev Biol Stand. 1977;39:341-6.
Ponies held in isolation for 40 months were vaccinated and revaccinated with four commercial equine influenza vaccines. Little or no HI antibody was detected after the first inoculation; second and subsequent annual revaccinations produced peak HI antibody titres between 7 and 14 days. Titres fell quickly between 14 and 28 days and less quickly thereafter. The decline of HI antibody appeared to be related more to the initial titre attained and to the period after vaccination than to the composition of the vaccine. The response to a first annual revaccination was superior to that produced by a second annual revaccination. Ether-treated antigens were required to identify primary and secondary responses to the equine-2-component of vaccines.
将隔离饲养40个月的小马用四种市售马流感疫苗进行初次接种和再次接种。首次接种后检测到很少或没有血凝抑制（HI）抗体；第二次及随后每年的再次接种在7至14天产生HI抗体滴度峰值。滴度在14至28天之间迅速下降，此后下降速度较慢。HI抗体的下降似乎更多地与达到的初始滴度和接种后的时间有关，而不是与疫苗的成分有关。首次年度再次接种的反应优于第二次年度再次接种。需要用乙醚处理的抗原来识别对疫苗中马2组分的初次和二次反应。
